While this article dates back to 2004 and references a different (yet more deadly – so far) form of Coronavirus – it bodes well for the efficacy of photobiomodulation (PBM) to assist with recovery from the current crisis. One of the primary effects of PBM is to release Nitric Oxide (NO) into the blood stream. Wouldn’t it be impressive if the simple act of using your Light Therapy Tools could stop the current crisis?
Nitric oxide (NO) is an important signaling molecule between cells which has been shown to have an inhibitory effect on some virus infections. The purpose of this study was to examine whether NO inhibits the replication cycle of the severe acute respiratory syndrome coronavirus (SARS CoV) in vitro. We found that an organic NO donor, S-nitroso-N-cetylpenicillamine, significantly inhibited the replication cycle of SARS CoV in a concentration-dependent manner. We also show here that NO inhibits viral protein and RNA synthesis. Furthermore, we demonstrate that NO generated by inducible nitric oxide synthase, an enzyme that produces NO, inhibits the SARS CoV replication cycle.
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